The Sandon River flows through Yuraygir National Park into the sea between Brooms Head and Wooli on the New South Wales north coast. The entrance is flanked by two rocky headlands which act as natural training walls. This estuary is classed as a medium-sized barrier river.
The Sandon River represents a relatively undisturbed system. Most of the catchment is protected under national park management or managed by forestry. Candole Creek and Toumbaal Creek converge with the Sandon River to form the lower estuary where extensive tidal flats provide abundant habitat for shorebirds and crustaceans.